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STXBP1 Antikörper (AA 11-110)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STXBP1 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN751663

Kurzübersicht für STXBP1 Antikörper (AA 11-110) (ABIN751663)

Target

Alle STXBP1 Antikörper anzeigen
STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reaktivität

  • 54
  • 43
  • 35
  • 7
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Ratte

Wirt

  • 61
  • 7
  • 2
Kaninchen

Klonalität

  • 61
  • 9
Polyklonal

Konjugat

  • 43
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser STXBP1 Antikörper ist unkonjugiert

Applikation

  • 54
  • 28
  • 18
  • 14
  • 12
  • 12
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-110

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Pig,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Munc18

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

    Andere Bezeichnung

    STXBP1/Munc18

    Hintergrund

    Synonyms: Munc 18 1, Munc 18a, NSec1, p67, Rb sec1, STXBP1, Syntaxin binding protein 1, Unc 18 homolog, Unc 18A, Unc18 1, STXB1_HUMAN, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.

    Background: Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.

    Gen-ID

    6812

    UniProt

    P61764

    Pathways

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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