Myoferlin Antikörper (AA 175-2003) (Fluoro488)

Produktnummer ABIN8012568

Der Kaninchen Polyklonal anti-Myoferlin Antikörper wird verwendet zum Nachweis von Myoferlin in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für Myoferlin Antikörper (AA 175-2003) (Fluoro488) (ABIN8012568)

Target: Myoferlin (MYOF)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myoferlin Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Myoferlin Antikörper (Fluoro488)

Bindungsspezifität: AA 175-2003

Verwendungszweck: Anti-MYOF Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MYOF recombinant protein (Position: E175-E2003). Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Myoferlin

Target: Myoferlin (MYOF)

Andere Bezeichnung: MYOF

Hintergrund:

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Gene Full Name: myoferlin

Gen-ID: 26509

UniProt: Q9NZM1