Myoferlin Antikörper (C-Term)

Produktnummer ABIN2782797

Der Kaninchen Polyklonal anti-Myoferlin Antikörper wird verwendet zum Nachweis von Myoferlin in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für Myoferlin Antikörper (C-Term) (ABIN2782797)

Target: Myoferlin (MYOF)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myoferlin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Myoferlin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FER1L3 Antibody - C-terminal region

Sequenz: QTEFRIPPRL IIQIWDNDKF SLDDYLGFLE LDLRHTIIPA KSPEKCRLDM

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FER1L3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FER1L3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46953-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Myoferlin

Target: Myoferlin (MYOF)

Andere Bezeichnung: FER1L3

Hintergrund:

Background Information: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. FER1L3 is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length natures have not been determined.

Gene Name: Myoferlin

Alternative Symbols: FER1L3

Protein Name: Myoferlin

Molekulargewicht: 235 kDa

Gen-ID: 26509

NCBI Accession: NP_038479

UniProt: Q9NZM1