MESDC2 Antikörper (AA 80-205) (Fluoro488)

Produktnummer ABIN8009190

Der Kaninchen Polyklonal anti-MESDC2 Antikörper wird verwendet zum Nachweis von MESDC2 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für MESDC2 Antikörper (AA 80-205) (Fluoro488) (ABIN8009190)

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MESDC2 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MESDC2 Antikörper (Fluoro488)

Bindungsspezifität: AA 80-205

Verwendungszweck: Anti-MESDC2/MESD Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MESDC2/MESD recombinant protein (Position: D80-Q205).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Andere Bezeichnung: MESD

Hintergrund:

Background: Mesoderm development candidate genes 1 (MESDC1) and 2 (MESDC2) were identified from the mesoderm development (MESD) deletion interval located on mouse chromosome 7. MESD acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6. MESD is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. The interaction between MESD and LRP5 is disrupted by a G171V mutation in LRP5 that is found in individuals with a familial phenotype characterized by high bone mass.

Gene Full Name: mesoderm development LRP chaperone

Gen-ID: 23184

UniProt: Q14696