MESDC2 Antikörper (Internal Region)

Produktnummer ABIN6263227

Produktdetails anti-MESDC2 Antikörper

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MESDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: MESDC2 Antibody detects endogenous levels of total MESDC2.

Homologie: Zebrafish,Bovine,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MESDC2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Andere Bezeichnung: MESDC2 (MESDC2 Produkte)

Synonyme: MGC115616 antikoerper, MESDC2 antikoerper, BOCA antikoerper, MESD antikoerper, 2210015O11Rik antikoerper, AW537813 antikoerper, mKIAA0081 antikoerper, mesd antikoerper, msd antikoerper, zgc:158636 antikoerper, mesoderm development LRP chaperone antikoerper, mesoderm development LRP chaperone L homeolog antikoerper, mesoderm development candidate 2 antikoerper, MESD antikoerper, mesd.L antikoerper, CpipJ_CPIJ010816 antikoerper, Tsp_04045 antikoerper, mesd antikoerper, Mesd antikoerper, MESDC2 antikoerper

Hintergrund:

Description: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).

Gene: MESDC2

Molekulargewicht: 26 kDa

Gen-ID: 23184

UniProt: Q14696