LIG3 Antikörper (AA 297-963) (Cy3)

Produktnummer ABIN8005976

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LIG3 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für LIG3 Antikörper (AA 297-963) (Cy3) (ABIN8005976)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG3 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LIG3 Antikörper (Cy3)

Bindungsspezifität: AA 297-963

Verwendungszweck: Anti-DNA Ligase III/LIG3 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DNA Ligase III/LIG3 recombinant protein (Position: D297-D963).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Andere Bezeichnung: LIG3

Hintergrund:

Background: DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: DNA ligase 3

Gen-ID: 3980

UniProt: P49916

Pathways: DNA Reparatur