LRRC59 Antikörper (AA 20-307) (FITC)

Produktnummer ABIN8005539

Der Kaninchen Polyklonal anti-LRRC59 Antikörper wird verwendet zum Nachweis von LRRC59 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für LRRC59 Antikörper (AA 20-307) (FITC) (ABIN8005539)

Target: LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC59 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LRRC59 Antikörper (FITC)

Bindungsspezifität: AA 20-307

Verwendungszweck: Anti-LRRC59 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC59 recombinant protein (Position: L20-Q307).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LRRC59

Target: LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))

Andere Bezeichnung: LRRC59

Hintergrund:

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene Full Name: leucine rich repeat containing 59

Gen-ID: 55379

UniProt: Q96AG4