Lamin B1 Antikörper (AA 266-583)

Produktnummer ABIN8005016

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Lamin B1 in WB, IHC, IP, ICC, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Lamin B1 Antikörper (AA 266-583) (ABIN8005016)

Target: Lamin B1 (LMNB1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-Lamin B1 Antikörper

Bindungsspezifität: AA 266-583

Verwendungszweck: Anti-Lamin B1/LMNB1 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Lamin B1 shares 95.9%,95% amino acid (aa) sequence identity with mouse,rat Lamin B1,respectively.

Produktmerkmale: Anti-Lamin B1/LMNB1 Antibody. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Lamin B1 recombinant protein (Position: Q266-C583). Human Lamin B1 shares 95.9% and 95% amino acid (aa) sequence identity with mouse and rat Lamin B1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Immunoprecipitation, 0.5-2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: LMNB1

Hintergrund:

Background: Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Gene Full Name: lamin B1

Sequence Similarities: Belongs to the intermediate filament family.

Molekulargewicht: 67 kDa

Gen-ID: 4001

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose