Kallikrein 8 Antikörper (AA 33-260)

Produktnummer ABIN8003937

Der Kaninchen Polyklonal anti-Kallikrein 8 Antikörper wird verwendet zum Nachweis von Kallikrein 8 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Kallikrein 8 Antikörper (AA 33-260) (ABIN8003937)

Target: Kallikrein 8 (KLK8)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Produktdetails anti-Kallikrein 8 Antikörper

Bindungsspezifität: AA 33-260

Verwendungszweck: Anti-Kallikrein 8/KLK8 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Kallikrein 8 shares 74%,73.1% amino acid (aa) sequence identity with mouse,rat Kallikrein 8,respectively.

Produktmerkmale: Anti-Kallikrein 8/KLK8 Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Kallikrein 8

Target: Kallikrein 8 (KLK8)

Andere Bezeichnung: KLK8

Hintergrund:

Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: kallikrein related peptidase 8

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Molekulargewicht: 28 kDa

Gen-ID: 11202

UniProt: O60259

Pathways: Komplementsystem