Kallikrein 8 Antikörper (AA 33-260) (Fluoro594)

Produktnummer ABIN8003931

Der Kaninchen Polyklonal anti-Kallikrein 8 Antikörper wird verwendet zum Nachweis von Kallikrein 8 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Kallikrein 8 Antikörper (AA 33-260) (Fluoro594) (ABIN8003931)

Target: Kallikrein 8 (KLK8)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 8 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Kallikrein 8 Antikörper (Fluoro594)

Bindungsspezifität: AA 33-260

Verwendungszweck: Anti-Kallikrein 8/KLK8 Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Kallikrein 8 shares 74%,73.1% amino acid (aa) sequence identity with mouse,rat Kallikrein 8,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Kallikrein 8

Target: Kallikrein 8 (KLK8)

Andere Bezeichnung: KLK8

Hintergrund:

Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: kallikrein related peptidase 8

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gen-ID: 11202

UniProt: O60259

Pathways: Komplementsystem