Kallikrein 7 Antikörper (AA 30-238) (HRP)

Produktnummer ABIN8003922

Der Kaninchen Polyklonal anti-Kallikrein 7 Antikörper wird verwendet zum Nachweis von Kallikrein 7 in Proben von Ratte. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für Kallikrein 7 Antikörper (AA 30-238) (HRP) (ABIN8003922)

Target: Kallikrein 7 (KLK7)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 7 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Kallikrein 7 Antikörper (HRP)

Bindungsspezifität: AA 30-238

Verwendungszweck: Anti-Klk7 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat Klk7 recombinant protein (Position: K30-N238).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Kallikrein 7

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: Klk7

Hintergrund:

Background: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions

Gene Full Name: kallikrein 1

Gen-ID: 292852

UniProt: P36373

Pathways: Komplementsystem