Kallikrein 10 Antikörper (C-Term) (APC)

Produktnummer ABIN8003846

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Kallikrein 10 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Kallikrein 10 Antikörper (C-Term) (APC) (ABIN8003846)

Target: Kallikrein 10 (KLK10)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 10 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Kallikrein 10 Antikörper (APC)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Kallikrein 10/KLK10 Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Kallikrein 10

Target: Kallikrein 10 (KLK10)

Andere Bezeichnung: KLK10

Hintergrund:

Background: KLK10 (kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The KLK10 gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al. (1997) mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis, Gan et al. (2000) mapped the KLK10 gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

Gene Full Name: kallikrein related peptidase 10

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Gen-ID: 5655

UniProt: O43240

Pathways: Komplementsystem