Kallikrein 1 Antikörper (AA 25-261) (Biotin)

Produktnummer ABIN8003828

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Kallikrein 1 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Kallikrein 1 Antikörper (AA 25-261) (Biotin) (ABIN8003828)

Target: Kallikrein 1 (KLK1)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Kallikrein 1 Antikörper (Biotin)

Bindungsspezifität: AA 25-261

Verwendungszweck: Anti-Kallikrein 1/KLK1 Antibody Biotin Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Kallikrein 1

Target: Kallikrein 1 (KLK1)

Andere Bezeichnung: KLK1

Hintergrund:

Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Gene Full Name: kallikrein 1

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Gen-ID: 16612

UniProt: P15947

Pathways: Komplementsystem