Kallikrein 1 Antikörper (AA 25-262) (HRP)

Produktnummer ABIN8003790

Der Kaninchen Polyklonal anti-Kallikrein 1 Antikörper wird verwendet zum Nachweis von Kallikrein 1 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für Kallikrein 1 Antikörper (AA 25-262) (HRP) (ABIN8003790)

Target: Kallikrein 1 (KLK1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Kallikrein 1 Antikörper (HRP)

Bindungsspezifität: AA 25-262

Verwendungszweck: Anti-Kallikrein 1/KLK1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Kallikrein 1 recombinant protein (Position: I25-S262).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Kallikrein 1

Target: Kallikrein 1 (KLK1)

Andere Bezeichnung: KLK1

Hintergrund:

Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Gene Full Name: kallikrein 1

Gen-ID: 3816

UniProt: P06870

Pathways: Komplementsystem