ISL1 Antikörper (AA 118-289) (Cy3)

Produktnummer ABIN8003334

Der Kaninchen Polyklonal anti-ISL1 Antikörper wird verwendet zum Nachweis von ISL1 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für ISL1 Antikörper (AA 118-289) (Cy3) (ABIN8003334)

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ISL1 Antikörper (Cy3)

Bindungsspezifität: AA 118-289

Verwendungszweck: Anti-Islet 1/ISL1 Antibody Cy3 Conjugated

Homologie: Human Islet 1,ISL1 shares 100% amino acid (aa) sequence identity with both mouse,rat ISL1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ISL1 recombinant protein (Position: D118-Q289). Human Islet 1/ISL1 shares 100% amino acid (aa) sequence identity with both mouse and rat ISL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Andere Bezeichnung: ISL1

Hintergrund:

Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Gene Full Name: ISL LIM homeobox 1

Gen-ID: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding