IFT74 Antikörper (AA 1-375)

Produktnummer ABIN8003145

Der Kaninchen Polyklonal anti-IFT74 Antikörper wird verwendet zum Nachweis von IFT74 in Proben von Human, Ratte, Maus und Affe. Er wurde validiert für ELISA, WB, IHC und FACS.

Kurzübersicht für IFT74 Antikörper (AA 1-375) (ABIN8003145)

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFT74 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-IFT74 Antikörper

Bindungsspezifität: AA 1-375

Verwendungszweck: Anti-IFT74 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Produktmerkmale: Anti-IFT74 Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IFT74

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Andere Bezeichnung: IFT74

Hintergrund:

Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

Gene Full Name: intraflagellar transport 74

Molekulargewicht: 69 kDa

Gen-ID: 80173

UniProt: Q96LB3

Pathways: Hedgehog Signalweg, Chromatin Binding