IFT74 Antikörper (AA 1-375) (Fluoro647)

Produktnummer ABIN8003144

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IFT74 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus und Affe.

Kurzübersicht für IFT74 Antikörper (AA 1-375) (Fluoro647) (ABIN8003144)

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFT74 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-IFT74 Antikörper (Fluoro647)

Bindungsspezifität: AA 1-375

Verwendungszweck: Anti-IFT74 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu IFT74

Target: IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

Andere Bezeichnung: IFT74

Hintergrund:

Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

Gene Full Name: intraflagellar transport 74

Gen-ID: 80173

UniProt: Q96LB3

Pathways: Hedgehog Signalweg, Chromatin Binding