IL-7 Antikörper (AA 26-154) (Fluoro488)

Produktnummer ABIN8002818

Der Kaninchen Polyklonal anti-IL-7 Antikörper wird verwendet zum Nachweis von IL-7 in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für IL-7 Antikörper (AA 26-154) (Fluoro488) (ABIN8002818)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-7 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-IL-7 Antikörper (Fluoro488)

Bindungsspezifität: AA 26-154

Verwendungszweck: Anti-IL7 Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4%,87.6% amino acid (aa) sequence identity with human,rat IL7,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4% and 87.6% amino acid (aa) sequence identity with human and rat IL7, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Andere Bezeichnung: Il7

Hintergrund:

Background: Interleukin 7  (IL-7) is a protein that in humans is encoded by the IL7 gene. The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. And it is found to be a cofactor for V (D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. In addition, this cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Gene Full Name: interleukin 7

Gen-ID: 16196

UniProt: P10168

Pathways: JAK-STAT Signalweg