CYBA Antikörper (AA 21-120)

Produktnummer ABIN750538

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CYBA in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für CYBA Antikörper (AA 21-120) (ABIN750538)

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CYBA Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CK18 Cytochrome b245 Light Chain/p22phox

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CYBA Antikörper (ABIN750538)

Song, Zhang, Han, Zhang, Zhang, Gao, Zhang, Chu, Zhao: "Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 945-956, (2019) (PubMed).

Yue, Wang, Wang, Du, Shen, Tang, Wang, Yin: "Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways." in: International journal of biological macromolecules, Vol. 89, pp. 376-88, (2016) (PubMed).

Yoshida, Murayama, Kawashima, Nagahara, Kangawa, Mizukami, Kimura, Abe, Hayashi, Shibutani: "Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, Vol. 69, Issue 1, pp. 9-16, (2016) (PubMed).

Li, Wang, Zhu, Zhang, Pan, Wang et al.: "Arctigenin suppresses transforming growth factor-?1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen ..." in: Free radical research, Vol. 49, Issue 9, pp. 1095-113, (2015) (PubMed).

Walton, Shin, Tajinda, Heusner, Kogan, Miyake, Chen, Tamura, Matsumoto: "Adult neurogenesis transiently generates oxidative stress." in: PLoS ONE, Vol. 7, Issue 4, pp. e35264, (2012) (PubMed).

Details zu CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Andere Bezeichnung: Cytochrome b245 Light Chain

Hintergrund:

Synonyms: p22-PHOX, Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22phox, CYBA

Background: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Gen-ID: 1535

UniProt: P13498

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis