IL-13 Antikörper (AA 22-131) (Fluoro550)
Kurzübersicht für IL-13 Antikörper (AA 22-131) (Fluoro550) (ABIN8001840)
Target
Alle IL-13 (IL13) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 22-131
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Verwendungszweck
- Anti-Interleukin-13 IL13 Antibody Fluoro550 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62%,76% amino acid (aa) sequence identity with human,mouse IL-13,respectively.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E. coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL-13, respectively.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- IL-13 (IL13) (Interleukin 13 (IL13))
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Andere Bezeichnung
- IL13
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Hintergrund
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Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
Gene Full Name: interleukin 13
Sequence Similarities: Belongs to the IL-4/IL-13 family.
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Gen-ID
- 116553
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UniProt
- P42203
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
Target
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