RORC Antikörper

Produktnummer ABIN750298

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RORC in WB, IHC (p) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RORC Antikörper (ABIN750298)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RORC Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ROR Gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: Ror gamma/rorc

Hintergrund:

Synonyms: NR1F3, Nuclear receptor ROR gamma, Nuclear receptor ROR-gamma, Nuclear receptor RZR gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR related orphan receptor C, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, Retinoic acid binding receptor gamma, Retinoid related orphan receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, RORG, RZR GAMMA, RZRG, TOR.

Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Gen-ID: 6097

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway