CHRDL2 Antikörper (AA 351-429) (Cy3)

Produktnummer ABIN750256

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHRDL2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für CHRDL2 Antikörper (AA 351-429) (Cy3) (ABIN750256)

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRDL2 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CHRDL2 Antikörper (Cy3)

Bindungsspezifität: AA 351-429

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHRDL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CHRDL2

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Andere Bezeichnung: CHRDL2

Hintergrund:

Synonyms: BNF1, Breast tumor novel factor 1, CHL2, chordin like 2, Chordin like protein 2 precursor, Chordin related protein 2, CRDL2_HUMAN.

Background: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.

Gen-ID: 25884