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CHRDL2 Antikörper

CHRDL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7190246
  • Target Alle CHRDL2 Antikörper anzeigen
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    Reaktivität
    • 17
    • 16
    • 13
    • 1
    Human
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHRDL2 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of Human CHRDL2
    Isotyp
    IgG
    Top Product
    Discover our top product CHRDL2 Primärantikörper
  • Applikationshinweise
    ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    Andere Bezeichnung
    CHRDL2 (CHRDL2 Produkte)
    Synonyme
    BNF1 antikoerper, CHL2 antikoerper, FKSG37 antikoerper, 1810022C01Rik antikoerper, Chl2 antikoerper, chl antikoerper, si:dkey-11j5.7 antikoerper, si:dkey-11j5.7-like antikoerper, chordin like 2 antikoerper, chordin-like 2 antikoerper, CHRDL2 antikoerper, Chrdl2 antikoerper, chrdl2 antikoerper
    Hintergrund

    Background: CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.

    Aliases: BNF-1 antibody, BNF1 antibody, Breast tumor novel factor 1 antibody, CHL2 antibody, chordin like 2 antibody, Chordin like protein 2 precursor antibody, Chordin related protein 2 antibody, Chordin-like protein 2 antibody, Chordin-related protein 2 antibody, Chrdl2 antibody, CRDL2_HUMAN antibody, DKFZp586N2124 antibody, FKSG37 antibody

    UniProt
    Q6WN34
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