HBEGF Antikörper (AA 63-148) (HRP)

Produktnummer ABIN7997051

Der HRP-konjugierte Kaninchen Polyklonal anti-HBEGF Antikörper (ABIN7997051) detektiert spezifisch HBEGF in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für HBEGF Antikörper (AA 63-148) (HRP) (ABIN7997051)

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBEGF Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-HBEGF Antikörper (HRP)

Bindungsspezifität: AA 63-148

Verwendungszweck: Anti-Hbegf Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Hbegf recombinant protein (Position: D63-L148).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Andere Bezeichnung: Hbegf

Hintergrund:

Background: Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. Enables epidermal growth factor receptor binding activity, growth factor activity, and heparin binding activity. Involved in positive regulation of keratinocyte migration, positive regulation of smooth muscle cell proliferation, and wound healing, spreading of epidermal cells. Acts upstream of or within several processes, including epidermal growth factor receptor signaling pathway, positive regulation of peptidyl-tyrosine phosphorylation, and regulation of heart contraction. Located in extracellular space. Is integral component of plasma membrane. Is expressed in several structures, including branchial arch, heart, oral region gland, telencephalon, and tooth. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).

Gene Full Name: heparin-binding EGF-like growth factor

Gen-ID: 15200

UniProt: Q06186

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung