HCK Antikörper (AA 14-501)

Produktnummer ABIN7996967

Der Kaninchen Polyklonal anti-HCK Antikörper (ABIN7996967) detektiert spezifisch HCK in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für HCK Antikörper (AA 14-501) (ABIN7996967)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-HCK Antikörper

Bindungsspezifität: AA 14-501

Verwendungszweck: Anti-HCK Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human HCK shares 89.2%,88.7% amino acid (aa) sequence identity with mouse,rat HCK,respectively.

Produktmerkmale: Anti-HCK Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HCK recombinant protein (Position: R14-R501). Human HCK shares 89.2% and 88.7% amino acid (aa) sequence identity with mouse and rat HCK, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Andere Bezeichnung: HCK

Hintergrund:

Background: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Gene Full Name: HCK proto-oncogene, Src family tyrosine kinase

Molekulargewicht: 60 kDa

Gen-ID: 3055

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling