HSPA6 Antikörper (C-Term) (Fluoro550)

Produktnummer ABIN7996443

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HSPA6 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HSPA6 Antikörper (C-Term) (Fluoro550) (ABIN7996443)

Target: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPA6 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HSPA6 Antikörper (Fluoro550)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-HSPA6 Antibody Fluoro550 Conjugated

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA6, which shares 81.2% amino acid (aa) sequence identity with mouse and rat HSPA6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HSPA6

Target: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Andere Bezeichnung: HSPA6

Hintergrund:

Background: Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene. The HSPA6 gene, also known as heat shock 70 kDa protein 6, encodes a member of the heat shock protein 70 (HSP70) family, which functions as molecular chaperones involved in protein folding, unfolding, and transport under stress conditions. HSPA6 is induced in response to cellular stressors such as heat shock, oxidative stress, and exposure to toxic agents, where it assists in protein refolding and prevents protein aggregation, thus promoting cell survival. While HSPA6 shares significant sequence homology with other HSP70 family members, it exhibits distinct expression patterns and functional properties in different tissues and cellular contexts. Its role in various physiological processes and diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases, is under investigation. Understanding the molecular mechanisms underlying HSPA6 function is crucial for elucidating its role in cellular stress responses and its potential as a therapeutic target for stress-related diseases.

Gene Full Name: heat shock protein family A (Hsp70) member 6

Gen-ID: 3310

UniProt: P17066