HAX1 Antikörper (AA 1-279) (PE)

Produktnummer ABIN7996096

Der Kaninchen Polyklonal anti-HAX1 Antikörper wird verwendet zum Nachweis von HAX1 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für HAX1 Antikörper (AA 1-279) (PE) (ABIN7996096)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAX1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HAX1 Antikörper (PE)

Bindungsspezifität: AA 1-279

Verwendungszweck: Anti-HAX1 Antibody PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HAX1 recombinant protein (Position: M1-R279).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1

Hintergrund:

Background: HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: HCLS1 associated protein X-1

Gen-ID: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization