GSTM2 Antikörper (Middle Region) (HRP)

Produktnummer ABIN7994344

Der Kaninchen Polyklonal anti-GSTM2 Antikörper wird verwendet zum Nachweis von GSTM2 in Proben von Ratte und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für GSTM2 Antikörper (Middle Region) (HRP) (ABIN7994344)

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-GSTM2 Antikörper (HRP)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-GSTM2 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse GSTM2. Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GSTM2

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Andere Bezeichnung: GSTM2

Hintergrund:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Gene Full Name: glutathione S-transferase, mu 2

Gen-ID: 14863

UniProt: P15626

Pathways: Negative Regulation of Transporter Activity