GBA3 Antikörper (AA 17-469) (HRP)

Produktnummer ABIN7993549

Der Kaninchen Polyklonal anti-GBA3 Antikörper wird verwendet zum Nachweis von GBA3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für GBA3 Antikörper (AA 17-469) (HRP) (ABIN7993549)

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GBA3 Antikörper (HRP)

Bindungsspezifität: AA 17-469

Verwendungszweck: Anti-GBA3 Antibody HRP Conjugated

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GBA3 recombinant protein (Position: Q17-L469).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3

Hintergrund:

Background: Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene. The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: glucosylceramidase beta 3 (gene/pseudogene)

Gen-ID: 57733

UniProt: Q9H227