GBA3 Antikörper (AA 17-469) (Cy3)

Produktnummer ABIN7993544

Der Cy3-konjugierte Kaninchen Polyklonal anti-GBA3 Antikörper (ABIN7993544) detektiert spezifisch GBA3 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GBA3 Antikörper (AA 17-469) (Cy3) (ABIN7993544)

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GBA3 Antikörper (Cy3)

Bindungsspezifität: AA 17-469

Verwendungszweck: Anti-GBA3 Antibody Cy3 Conjugated

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GBA3 recombinant protein (Position: Q17-L469).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3

Hintergrund:

Background: Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene. The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: glucosylceramidase beta 3 (gene/pseudogene)

Gen-ID: 57733

UniProt: Q9H227