Gephyrin Antikörper (AA 148-736) (Fluoro488)

Produktnummer ABIN7993105

Der Kaninchen Polyklonal anti-Gephyrin Antikörper wird verwendet zum Nachweis von Gephyrin in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für FACS.

Kurzübersicht für Gephyrin Antikörper (AA 148-736) (Fluoro488) (ABIN7993105)

Target: Gephyrin (GPHN)

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Gephyrin Antikörper (Fluoro488)

Bindungsspezifität: AA 148-736

Verwendungszweck: Anti-Gephyrin/GPHN Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Gephyrin/GPHN recombinant protein (Position: K148-L736).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: GPHN

Hintergrund:

Background: Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Gene Full Name: gephyrin

Gen-ID: 10243

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development