Fibromodulin Antikörper (AA 19-376) (HRP)

Produktnummer ABIN7990792

Der Kaninchen Polyklonal anti-Fibromodulin Antikörper wird verwendet zum Nachweis von Fibromodulin in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Fibromodulin Antikörper (AA 19-376) (HRP) (ABIN7990792)

Target: Fibromodulin (FMOD)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibromodulin Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Fibromodulin Antikörper (HRP)

Bindungsspezifität: AA 19-376

Verwendungszweck: Anti-Fibromodulin/FMOD Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Fibromodulin,FMOD shares 93.3% amino acid (aa) sequence identity with both mouse,rat Fibromodulin,FMOD.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibromodulin/FMOD recombinant protein (Position: Q19-I376). Human Fibromodulin/FMOD shares 93.3% amino acid (aa) sequence identity with both mouse and rat Fibromodulin/FMOD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Fibromodulin

Target: Fibromodulin (FMOD)

Andere Bezeichnung: FMOD

Hintergrund:

Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Gene Full Name: fibromodulin

Gen-ID: 2331

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process