FGF1 Antikörper (AA 16-155) (HRP)

Produktnummer ABIN7990417

Der Kaninchen Polyklonal anti-FGF1 Antikörper wird verwendet zum Nachweis von FGF1 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für FGF1 Antikörper (AA 16-155) (HRP) (ABIN7990417)

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-FGF1 Antikörper (HRP)

Bindungsspezifität: AA 16-155

Verwendungszweck: Anti-Fibroblast growth factor 1 FGF1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human FGF1 recombinant protein (Position: F16-D155).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Andere Bezeichnung: FGF1

Hintergrund:

Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. Human FGF1 shares 96 % amino acid sequence homology with both rat and mouse. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is though to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.

Gene Full Name: fibroblast growth factor 1

Sequence Similarities: Belongs to the heparin-binding growth factors family.

Gen-ID: 2246

UniProt: P05230

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung