Fibrinogen beta Chain Antikörper (Middle Region)

Produktnummer ABIN7990344

Dieser Maus Monoklonal Antikörper detektiert spezifisch Fibrinogen beta Chain in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Fibrinogen beta Chain Antikörper (Middle Region) (ABIN7990344)

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Klon: 6D12

Produktdetails anti-Fibrinogen beta Chain Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-Fibrinogen beta chain/FGB Antibody (monoclonal, 6D12)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by three amino acids,and from the related rat sequence by five amino acids.

Produktmerkmale: Anti-Fibrinogen beta chain/FGB Antibody.(monoclonal, 6D12)-1. Tested in IHC, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human FGB, different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB

Hintergrund:

Background: Fibrinogen beta chain, mapped to 4q31.3, is also known asFGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: fibrinogen beta chain

Molekulargewicht: 56 kDa

Gen-ID: 2244

UniProt: P02675