FDPS Antikörper (AA 12-347) (HRP)

Produktnummer ABIN7989668

Der HRP-konjugierte Kaninchen Polyklonal anti-FDPS Antikörper (ABIN7989668) detektiert spezifisch FDPS in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte und Maus.

Kurzübersicht für FDPS Antikörper (AA 12-347) (HRP) (ABIN7989668)

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDPS Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-FDPS Antikörper (HRP)

Bindungsspezifität: AA 12-347

Verwendungszweck: Anti-FDPS/FPS Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse FDPS/FPS recombinant protein (Position: Q12-K347).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Andere Bezeichnung: Fdps

Hintergrund:

Background: Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene. It is mapped to 3 F1, 3 39.01 cM. This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: farnesyl diphosphate synthetase

Gen-ID: 110196

UniProt: Q920E5

Pathways: Regulation of Muscle Cell Differentiation