FDPS Antikörper (AA 29-397) (Cy3)

Produktnummer ABIN7989652

Der Kaninchen Polyklonal anti-FDPS Antikörper wird verwendet zum Nachweis von FDPS in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für FDPS Antikörper (AA 29-397) (Cy3) (ABIN7989652)

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDPS Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-FDPS Antikörper (Cy3)

Bindungsspezifität: AA 29-397

Verwendungszweck: Anti-FDPS/FPS Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FDPS/FPS recombinant protein (Position: S29-Q397).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Andere Bezeichnung: FDPS

Hintergrund:

Background: Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene. It is mapped to 1q22. This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: farnesyl diphosphate synthase

Gen-ID: 2224

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation