NFAM1 Antikörper (AA 81-180)
Kurzübersicht für NFAM1 Antikörper (AA 81-180) (ABIN749033)
Target
Alle NFAM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 81-180
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Pig,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human NFAM1
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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: "NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." in: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).
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: "NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." in: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).
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- NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
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Andere Bezeichnung
- NFAM1
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Hintergrund
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Synonyms: CNAIP, bK126B4.4, NFAT activation molecule 1, Calcineurin/NFAT-activating ITAM-containing protein, NFAT-activating protein with ITAM motif 1, NFAM1
Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
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Gen-ID
- 150372
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UniProt
- Q8NET5
Target
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