DUOX2 Antikörper (AA 63-403) (Biotin)

Produktnummer ABIN7986420

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DUOX2 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Ratte und Maus.

Kurzübersicht für DUOX2 Antikörper (AA 63-403) (Biotin) (ABIN7986420)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUOX2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-DUOX2 Antikörper (Biotin)

Bindungsspezifität: AA 63-403

Verwendungszweck: Anti-Duox2 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Duox2 recombinant protein (Position: A63-D403).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Andere Bezeichnung: Duox2

Hintergrund:

Background: Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Gene Full Name: dual oxidase 2

Gen-ID: 214593

UniProt: B7ZWM4

Pathways: Thyroid Hormone Synthesis