DNMT3B Antikörper (AA 17-572) (HRP)

Produktnummer ABIN7985813

Der HRP-konjugierte Kaninchen Polyklonal anti-DNMT3B Antikörper (ABIN7985813) detektiert spezifisch DNMT3B in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Affe.

Kurzübersicht für DNMT3B Antikörper (AA 17-572) (HRP) (ABIN7985813)

Target: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reaktivität: Human, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNMT3B Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-DNMT3B Antikörper (HRP)

Bindungsspezifität: AA 17-572

Verwendungszweck: Anti-DNMT3B Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DNMT3B recombinant protein (Position: R17-R572).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DNMT3B

Target: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Andere Bezeichnung: DNMT3B

Hintergrund:

Background: DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Gene Full Name: DNA methyltransferase 3 beta

Gen-ID: 1789

UniProt: Q9UBC3