DKK2 Antikörper (AA 34-259) (HRP)

Produktnummer ABIN7985173

Der Kaninchen Polyklonal anti-DKK2 Antikörper wird verwendet zum Nachweis von DKK2 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für DKK2 Antikörper (AA 34-259) (HRP) (ABIN7985173)

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKK2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DKK2 Antikörper (HRP)

Bindungsspezifität: AA 34-259

Verwendungszweck: Anti-DKK2 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DKK2 recombinant protein (Position: K34-I259). Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DKK2

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Andere Bezeichnung: DKK2

Hintergrund:

Background: Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).

Gene Full Name: dickkopf Wnt signaling pathway inhibitor 2

Sequence Similarities: Belongs to the DAXX family.

Gen-ID: 27123

UniProt: Q9UBU2

Pathways: WNT Signalweg