Desmocollin 2 Antikörper (AA 29-683) (Cy3)

Produktnummer ABIN7984955

Der Cy3-konjugierte Kaninchen Polyklonal anti-Desmocollin 2 Antikörper (ABIN7984955) detektiert spezifisch Desmocollin 2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Desmocollin 2 Antikörper (AA 29-683) (Cy3) (ABIN7984955)

Target: Desmocollin 2 (DSC2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 2 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Desmocollin 2 Antikörper (Cy3)

Bindungsspezifität: AA 29-683

Verwendungszweck: Anti-DSC2 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DSC2 recombinant protein (Position: S29-P683).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Desmocollin 2

Target: Desmocollin 2 (DSC2)

Andere Bezeichnung: DSC2

Hintergrund:

Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene Full Name: desmocollin 2

Gen-ID: 1824

UniProt: Q02487