CBS Antikörper (AA 331-551) (Fluoro594)

Produktnummer ABIN7982620

Der Kaninchen Polyklonal anti-CBS Antikörper wird verwendet zum Nachweis von CBS in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für CBS Antikörper (AA 331-551) (Fluoro594) (ABIN7982620)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBS Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CBS Antikörper (Fluoro594)

Bindungsspezifität: AA 331-551

Verwendungszweck: Anti-Cystathionine beta-synthase CBS Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CBS shares 83% amino acid (aa) sequence identity with both mouse,rat CBS.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Andere Bezeichnung: CBS

Hintergrund:

Background: Cystathionine-β-synthase, also known as CBS, is an enzyme that in humans is encoded by the CBS gene. It is mapped to 21q22.3 and contains 23 exons, ranging in size from 42 to 299 bp. CBS catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

Gene Full Name: cystathionine beta-synthase like

Sequence Similarities: Belongs to the cysteine synthase/cystathionine beta- synthase family.

Gen-ID: 875

UniProt: P35520