LAG3 Antikörper (PE-Cy7)
Kurzübersicht für LAG3 Antikörper (PE-Cy7) (ABIN748521)
Target
Alle LAG3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
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Isotyp
- IgG
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Applikationshinweise
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WB(1:100-500)
FCM(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)
IF(ICC)(1:100-500) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Andere Bezeichnung
- Lymphocyte Activation Gene 3
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Hintergrund
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Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3
Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
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Molekulargewicht
- 58kDa
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Gen-ID
- 297596
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UniProt
- Q5BK54
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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