CRB1 Antikörper (C-Term) (HRP)

Produktnummer ABIN7981861

Der Kaninchen Polyklonal anti-CRB1 Antikörper wird verwendet zum Nachweis von CRB1 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für CRB1 Antikörper (C-Term) (HRP) (ABIN7981861)

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRB1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CRB1 Antikörper (HRP)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-CRB1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CRB1, which shares 87.9% and 84.8% amino acid (aa) sequence identity with mouse and rat CRB1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CRB1

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Andere Bezeichnung: CRB1

Hintergrund:

Background: Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.

Gene Full Name: crumbs cell polarity complex component 1

Gen-ID: 23418

UniProt: P82279

Pathways: Notch Signalweg