CRB1 Antikörper (AA 780-830)

Produktnummer ABIN6991795

Produktdetails anti-CRB1 Antikörper

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Bindungsspezifität: AA 780-830

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRB1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.

Aufreinigung: CRB1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CRB1 antibody can be used for detection of CRB1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CRB1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CRB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu CRB1

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Andere Bezeichnung: CRB1 (CRB1 Produkte)

Synonyme: CRB1 antikoerper, si:dkey-114d20.6 antikoerper, si:dkey-114d20.7 antikoerper, LCA8 antikoerper, RP12 antikoerper, 7530426H14Rik antikoerper, A930008G09Rik antikoerper, crumbs 1, cell polarity complex component antikoerper, crumbs family member 1, photoreceptor morphogenesis associated antikoerper, CRB1 antikoerper, crb1 antikoerper, Crb1 antikoerper

Hintergrund: CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.

Molekulargewicht: Predicted: 142 kDa

Gen-ID: 23418

NCBI Accession: NP_001180569

UniProt: P82279

Pathways: Notch Signalweg