Cortactin Antikörper (AA 1-105) (APC)

Produktnummer ABIN7981719

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cortactin in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Cortactin Antikörper (AA 1-105) (APC) (ABIN7981719)

Target: Cortactin (CTTN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cortactin Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Cortactin Antikörper (APC)

Bindungsspezifität: AA 1-105

Verwendungszweck: Anti-Cortactin/CTTN Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Cortactin recombinant protein (Position: M1-Q105).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: CTTN

Hintergrund:

Background: Cortactin, mapped to 11q13.3, is a multidomain protein. This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Gene Full Name: cortactin

UniProt: Q14247

Pathways: MAPK Signalweg