C5 Antikörper (AA 1-77) (HRP)

Produktnummer ABIN7981388

Der HRP-konjugierte Kaninchen Polyklonal anti-C5 Antikörper (ABIN7981388) detektiert spezifisch C5 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für C5 Antikörper (AA 1-77) (HRP) (ABIN7981388)

Target: C5 (Complement Component 5 (C5))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-C5 Antikörper (HRP)

Bindungsspezifität: AA 1-77

Verwendungszweck: Anti-C5/C5a Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Rat C5a shares 62%,82% amino acid (aa) sequences identity with human,mouse C5a,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat C5a recombinant protein (Position: D1-R77). Rat C5a shares 62% and 82% amino acid (aa) sequences identity with human and mouse C5a, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: C5

Hintergrund:

Background: C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

Gene Full Name: complement component 5

Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family.

Gen-ID: 362119

UniProt: P08650

Pathways: Komplementsystem, Carbohydrate Homeostasis