M-CSF/CSF1 Antikörper (AA 33-262) (HRP)

Produktnummer ABIN7981256

Der HRP-konjugierte Kaninchen Polyklonal anti-M-CSF/CSF1 Antikörper (ABIN7981256) detektiert spezifisch M-CSF/CSF1 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für M-CSF/CSF1 Antikörper (AA 33-262) (HRP) (ABIN7981256)

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser M-CSF/CSF1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-M-CSF/CSF1 Antikörper (HRP)

Bindungsspezifität: AA 33-262

Verwendungszweck: Anti-MCSF/CSF1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 %,88.6% amino acid (aa) sequence identity with human,rat MCSF,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Andere Bezeichnung: Csf1

Hintergrund:

Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Gene Full Name: colony stimulating factor 1 (macrophage)

Sequence Similarities: Contains 5 cadherin domains.

Gen-ID: 12977

UniProt: P07141

Pathways: RTK Signalweg