Claudin 2 Antikörper (AA 63-230) (Cy3)

Produktnummer ABIN7980424

Der Kaninchen Polyklonal anti-Claudin 2 Antikörper wird verwendet zum Nachweis von Claudin 2 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Claudin 2 Antikörper (AA 63-230) (Cy3) (ABIN7980424)

Target: Claudin 2 (CLDN2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 2 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Claudin 2 Antikörper (Cy3)

Bindungsspezifität: AA 63-230

Verwendungszweck: Anti-Claudin 2/CLDN2 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CLDN2 recombinant protein (Position: Q63-V230).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Claudin 2

Target: Claudin 2 (CLDN2)

Andere Bezeichnung: CLDN2

Hintergrund:

Background: Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

Gene Full Name: claudin 2

Gen-ID: 9075

UniProt: P57739

Pathways: Hepatitis C