CNTF Antikörper (AA 2-200)

Produktnummer ABIN7980268

Der Kaninchen Polyklonal anti-CNTF Antikörper wird verwendet zum Nachweis von CNTF in Proben von Ratte und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für CNTF Antikörper (AA 2-200) (ABIN7980268)

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Güteklasse: Carrier-free

Produktdetails anti-CNTF Antikörper

Bindungsspezifität: AA 2-200

Verwendungszweck: Anti-CNTF Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84%,95% amino acid (aa) sequences identity with human,mouse CNTF,respectively.

Produktmerkmale: Anti-CNTF Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84% and 95% amino acid (aa) sequences identity with human and mouse CNTF, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, 0.1-0.5 μg/mL, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CNTF

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Andere Bezeichnung: CNTF

Hintergrund:

Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.

Gene Full Name: ciliary neurotrophic factor

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Molekulargewicht: 23 kDa

Gen-ID: 25707

UniProt: P20294

Pathways: JAK-STAT Signalweg